SCHEDULE: NOV 16-21, 2014

When viewing the Technical Program schedule, on the far righthand side is a column labeled "PLANNER." Use this planner to build your own schedule. Once you select an event and want to add it to your personal schedule, just click on the calendar icon of your choice (outlook calendar, ical calendar or google calendar) and that event will be stored there. As you select events in this manner, you will have your own schedule to guide you through the week.

ENTIRE WEEK SUNDAY MONDAY TUESDAY WEDNESDAY THURSDAY FRIDAY

A Molecular Model for Platelets at Multiple Scales and Simulations on Supercomputers

SESSION: ACM Student Research Competition Poster Reception

EVENT TYPE: ACM Student Research Competition

TIME: 5:15PM - 7:00PM

AUTHOR(S):Li Zhang

ROOM:New Orleans Theater Lobby

ABSTRACT:

A molecular model at multiscale for human platelets is designed and implemented on large-scale supercomputers. The model characterizes the principal physiological functions of key components of single platelet. The organelle zone centralizes as the cytoplasm, the peripheral zone includes the bilayer and exterior coats, and the cytoskeleton zone forms the flow-induced filopodia. It is the first time such a massive model in biomedical engineering is proposed and high-performance computing is the only potential solution for initial-understanding of the model. Algorithmically, a coarse-grained molecular dynamics force field describes the molecular-level interactions in the membrane and cytoskeleton while a Morse potential is applied to the cytoplasm. Together, a coarse-grained stochastic dynamics is applied to simulating the macroscopic viscous fluid flows. Numerical experiments with our model require considerations of large number of particles and the physiological phenomena at multiscale and thus demand development of the-state-of-the-art parallel algorithms, the main thrust of this research.